What is the problem with flu vaccine?


What is the problem with flu vaccine?

Common side effects from a flu shot include soreness, redness, and/or swelling where the shot was given, headache (low grade), fever, nausea, muscle aches, and fatigue.

What is the main challenge in creating a universal influenza vaccine?

A variety of immunogens have been tested on VLPs, including HA, matrix protein 2 (M2), and NA [44,45,46]. One of the main barriers to the use of this vaccine construct is the challenge of generating sufficient immunogenicity.

Is Fluenz Tetra a live vaccine?

Fluenz Tetra will contain live attenuated (weakened) influenza A and B virus strains (type A-H1N1, type A-H3N2, and two type B strains) based on the official recommendation for the annual flu season.

Why is it difficult to make vaccines for influenza?

In some years certain influenza viruses may not circulate until later in the influenza season, making it difficult to prepare a candidate vaccine virus in time for vaccine production. This can make vaccine virus selection very challenging.

Why must new influenza vaccines be developed annually?

It’s because new strains of the virus are constantly appearing and evolving, so the vaccine must change along with them. Located around the world are influenza surveillance centers that annually monitor the most common strains, collecting data and identifying new and evolving strains.

Is Fluenz Tetra safe?

How safe is Fluenz Tetra® and what are the side effects of having this vaccine? This vaccine is safe and has been used in the UK for the last two years and elsewhere for many years. Most people do not get side effects whilst others may get a few.

What are the limitations of the flu vaccine?

Vaccination is the most effective method to prevent influenza infection. However, current influenza vaccines have several limitations. Relatively long production times, limited vaccine capacity, moderate efficacy in certain populations and lack of cross-reactivity are important issues that need to be addressed.

Should I let my child have the flu vaccine?

In most cases, yes. The Centers for Disease Control and Prevention (CDC) recommends a yearly flu (influenza) vaccine for all children 6 months and older in the United States — ideally by the end of October. This year the CDC recommends the flu shot or the nasal spray flu vaccine.

How effective is Fluenz Tetra?

Fluenz demonstrated 55.7% (39.9, 67.6) fewer cases than injectable influenza vaccine in 3,686 infants and toddlers 6-23 months of age and 54.4% (41.8, 64.5) fewer cases in 4,166 children 24-59 months of age.