What is the chemical structure of acyclovir?


What is the chemical structure of acyclovir?

C8H11N5O3Aciclovir / Formula

What does acyclovir cream contain?

1g of Cream contains 50mg aciclovir. For excipients, see 6.1. Cream. White to off-white cream.

What is the difference between acyclovir cream and acyclovir ointment?

Acyclovir topical cream is used to treat cold sores on the lips and face. Acyclovir topical ointment is used to treat genital herpes lesions. There is no cure for herpes and acyclovir will not prevent you from developing symptoms in the future.

What is the mechanism of acyclovir?

Mechanism of Action: Acyclovir is converted to its triphosphate form, acyclovir triphosphate (ACV-TP), which competitively inhibits viral DNA polymerase, incorporates into and terminates the growing viral DNA chain, and inactivates the viral DNA polymerase.

What kind of compound is acyclovir?

Acyclovir is a synthetic analog of the purine nucleoside, guanosine, with potent antiviral activity against herpes simplex viruses type 1 and 2, varicella-zoster virus and other viruses of the herpesvirus family.

Why acyclovir is a prodrug?

This prodrug provides the opportunity to design regimes that are more convenient for the patient and may be more effective than acyclovir itself in the therapy of the less sensitive herpes viruses (e.g. Epstein-Barr virus and the Cytomegalovirus).

What does antiviral cream contain?

Each gram of cream contains Aciclovir 50 mg, which is the active ingredient. As well as the active ingredient, the cream also contains PEG-5-glycerol-stearate, dimeticone, cetyl alcohol, liquid paraffin, white soft paraffin, propylene glycol and purified water.

What is Acivir cream?

Acivir Cream is an antiviral medicine which helps in treating skin infections caused by Herpes simplex virus such as herpes labialis. It prevents the multiplication of the virus in skin cells and therefore helps in clearing the skin infection.

Is acyclovir cream or ointment better?

Conclusions In this model, the efficacy of penciclovir cream was greater than acyclovir cream, acyclovir cream was greater than or equal to acyclovir ointment, and acyclovir ointment was greater than n-docosanol cream.

How does acyclovir cream work?

Acyclovir is in a class of antiviral medications called synthetic nucleoside analogues. It works by stopping the spread of the herpes virus in the body. Acyclovir does not cure cold sores or genital herpes, does not prevent outbreaks of these conditions, and does not stop the spread of these conditions to other people.

What is the difference between acyclovir and acyclovir?

Valacyclovir (Valtrex) and acyclovir (Zovirax) are antiviral drugs that work by interfering with viral DNA replication. Both drugs target the same viruses but valacyclovir provides longer duration of action, therefore, doses can be taken fewer times every day – this is the only real advantage.

What does aciclovir cream do?

Acyclovir cream is used to treat cold sores (fever blisters; blisters that are caused by a virus called herpes simplex) on the face or lips.

Is aciclovir a prodrug?

Valaciclovir, the l-valyl ester of aciclovir, has been developed as a prodrug to improve bioavailability. Aciclovir is used in prophylaxis against herpesvirus infections in patients with leukopenia after chemotherapy for malignant diseases.

How is acyclovir metabolised?

Sequential oxidation reactions by alcohol dehydrogenase and aldehyde dehydrogenase metabolize acyclovir to CMMG, and aldehyde oxidase metabolizes acyclovir to 8-OH-ACV (10, 23).

What is aciclovir cream used for?

Can Acivir cream be used on vagina?

Aciclovir cream is not intended for use in your mouth or vagina, or near your eyes. This is because it may irritate these parts of your body. If you have sores in any of these areas, you should make an appointment to see your doctor, as alternative preparations can be prescribed which will be suitable for you to use.

What is antiviral cream?

Topical antiviral agents are applied locally to treat viral infections. Different antiviral agents have different mechanisms of action but they all inhibit production of viruses that cause disease. Topical agents are used to treat viral conditions such as cold sores (facial herpes simplex).

Can acyclovir cream be used on lips?

Acyclovir topical (for the skin) is an antiviral medicine that is used to treat skin symptoms caused by the herpes virus. Acyclovir topical cream is used to treat cold sores on the lips and face.