How does 2/4 dinitrophenol cause weight loss?

09/10/2022

How does 2/4 dinitrophenol cause weight loss?

DNP (2,4-Dinitrophenol) has a variety of industrial uses, including as a photographic chemical, a fertilizer and in the manufacturing of dyes and explosives. It causes weight loss by burning fat and carbohydrates, in turn causing energy to be converted into heat.

What do SDS sheets contain?

The SDS includes information such as the properties of each chemical; the physical, health, and environmental health hazards; protective measures; and safety precautions for handling, storing, and transporting the chemical.

What are the 16 sections of SDS?

Information in the SDS should be presented using the following 16 headings in the order given below:

  • Identification.
  • Hazard(s) identification.
  • Composition/information on ingredients.
  • First-aid measures.
  • Fire-fighting measures.
  • Accidental release measures.
  • Handling and Storage.
  • Exposure controls/personal protection.

What is DNP poison?

DNP is a metabolic poison that acts by uncoupling oxidative phosphorylation, leading to uncontrolled hyperthermia. It is an illegal weight loss agent that is used by body builders and is freely available on many internet websites. This case highlights the potential for patients to obtain and ingest exotic poisons.

Is dinitrophenol poisonous?

Dinitrophenols (C6-H4-N2-O4; Chemical Abstracts Service (CAS) No. 25550-58-7) are highly toxic chemicals with six isomeric compounds.

What are the 3 levels of hazard control?

Hazard Controls

  • Elimination and Substitution. The most preferred method of controlling risk is to eliminate the hazard altogether.
  • Engineering Controls.
  • Administrative Controls.
  • Personal Protective Equipment (PPE)

Is DNP a drug?

Due to the sheer number of deaths of patients who were prescribed DNP, in addition to the other common and horrific AEs DNP provided, the drug was banned in the United States in 1938 and declared unfit for human consumption.

How is DNP toxic?

The primary toxicity seen with DNP is similar to that seen with other phenol-based products and is a combination of hyperthermia, tachycardia, diaphoresis and tachypnoea with associated cardiovascular collapse/cardiac arrest and death.